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Diazepam is N-demethylated by CYP3A4 and 2C19 towards the Energetic metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 into the Lively metabolite temazepam. N-desmethyldiazepam and temazepam are both equally further metabolized to oxazepam. Temazepam and oxazepam are mostly removed by glucuronidation.Acute intoxication with alcohol, narc